Joe.T,
The Giants are missing 3 offensive starters (Nicks, Diehl, and Bradhsaw) and their #3 receiver and punt returner (Hixon) for tonight's game. On defense, starting CB Prince Amukamar returns. Giants need a big game from their D tonight. On offense, I look for the Panthers to double team the shit out of Cruz, meaning Eli will need to go to Martellus Bennett a lot. Ramses Barden, who has barely played in 3 years, starts at the other WR spot. He is big at 6'6" but has so so hands. Reuben Randle is the new #3 receiver, a rookie from LSU. Randle is 6'3" and has good size, and may see a lot of time.
Andre Brown starts at RB for the G Men. He played well last week, and the OL looked good last week, no sacks in 51 pass plays, how about that Joe?
Your pick is not unreasonable, but I think the Giants will foil your pick with a big game from the D.