EB, people in general should not listen to mad scientists in a white lab coat coming on MERB and Twitter (TL...lol) giving advice and making predictions about the corona virus!
Coronavirus
- Thread starter C.B. Brown
- Start date
I respectfully disagree. Trump (and today his lawyer Guliani) continue to deliberately spread misinformation. Trump blatantly attempted to influence vendors not to supply medical equipment to states whose governors declined to compliment him. His description of the virus as Chinese most probably provided the impetus for the scapegoating of some American residents of Asiastic origin.
It is only in response to criticism that some of his current stupidities are being mitigated.
Why not look at Gov. Cuomo and all his NY Team of leaders who themselves DOWNPLAYED this virus and told New Yorkers all through January and late into February how they should go enjoy a dinner out, ride the subway ... etc ... nothing to see here folks! Now its all the PResident's fault ... love a good lib when they use both sides of their mouth ...
The postus should lead by example. Trump today on Twitter praised the audience rating of his press conference. What else do you need to realize that this ass hole is unfit to lead such a crisis? Nurse are going to work short of supplies.
Get this fucking jerk out of the way please!
Does anyone know why our province has over 40% of Canada’s total cases ?
Is it because they are indeed testing more people , or because they were much slower in declaring a state of emergency than the rest of the province’s?
I was trying to get some inside information from him. After we talked about my personal issues I was there to see him about, I started the conversation off by asking that very question- whether he would be a very busy man in a few months. He cited a lot of data to me about common influenza, and suggested to me that Covid-19 was maybe slightly worse than a new strain of flu but totally unworthy of the media attention it was receiving. I was surprised by his comments, and I would suggest that the people in this thread who are posting that Trump did not listen to medical experts are misguided, because I think this is what a lot of medical experts were thinking. This guy basically told me what Trump said 2 months later.
By way of full disclosure, I had a confirmed viral pneumonia in April 2019. I worked through it, but it was no picnic, and I ended up with a chronic dry cough that would not go away. I saw the pulmonologist about it and he ran some tests, including a CT scan and a bronchoscopy which showed my lungs and respiratory system to be completely normal. He prescribed 3 different inhalers, none of which worked at all, and then prescribed 2 different nasal sprays, which did help, suggesting that the problem was due to some post-nasal drip. I did have a sinus surgery in 2000, this the result of a badly broken nose sustained while playing softball. After that injury I had to have an initial surgery to put my nose back together, and then a second surgery on the sinuses because I kept getting sinus infections- the 2nd surgery was to wide the sinus passage going to my throat because the infections were due to the drainage system being clogged. Or so my ENT surgeon told me at that time. I think when I had the viral pneumonia it somehow must have aggravated this pre-existing situation.
I actually like him, he is around 40 or so and younger than me, and does seem like he cares. But the opinion he gave me was one I think was a consensus among his peers and he was very angry about Coronavirus being spotlighted -at the time it was just in China- while common influenza had killed a lot of people in Connecticut with no media attention at all. I believe he hated the discrimination and bias in favor of one virus over another, not surprising perhaps because he is a visible minority himself. Now, however, he is probably quite busy because his patients are mostly the exact kinds of people with pre-existing respiratory conditions and ailments that makes them potentially fatal victims of C-19. I saw lots of patients in his office who needed oxygen intubation and ventilators even before Covid-19 came to the USA.
my buddy’s an ICU doc in USA. Was shooting hoops with the lads 3 days ago when I called him, lol. His city isn’t on lockdown but are advocating social distancing
What are you talking about? It is closed, except for essential services. (supply chains and such)
I think he meant close the border 100%, meaning the supply chain umbilical cord from the USA is severed and Quebec fends for itself with it own products, 100%, and nothing else.
Lol! St-TL prier pour nous pauvre pêcheurs et faite que la crise du covid-19 passe vite pour qu'on puisse s'occuper de nos ptite mère et arrêter de spéculé! Amen! 
Just remember they don't grow oranges in Quebec, so once the US supply chain is cut, forget about the OJ for breakfast, dude. Also forget about the Grapefruit Juice. Your ass is gonna be drinking canned prune juice for breakfast.
At the moment they are, it was said by Legault.
From my understanding right now we still get test result from peoples who got infected 1 week + ago, some travelers who are still coming back, and so on. My hopes are that by mid-April the "curve" has really flattened because why would peoples still get infected with the world on shutdown?
That being said tough peoples like my neighbors still keep receiving friends at his app, so i supose he ain't the only one doing it... probably a lot of tick headed peoples who don't follow the "orders"
From what i understand its the problem in Italy and New York even at the moment. A lot of peoples COULD survive but die because decisions are made to heal other patients who are younger, have better chances to live etc. The system is overload and can't process everybody. Wich at the moment is alright in Quebec because they could threat 6000 patients i think, but only 200 less are in hospital.
As i said above, the full lockdown didn't started until what, a week ago, not even? Yes some stuff closed on March 16 but not a lot. So it may take another 2 weeks from today to fully feel the curve flattening.
As for border, im not an expert so i can't know exactly how many products come from the E-U but my understanding is the products themselves are not at risk, only the delivery person who does it, so if he is carefull and follow protocol, it should be fine. I mean yes i eat an orange everyday at breakfast and yes i could live without it for a few months, but it may be a lot more than just a couple things like that.
Anyway, i think we can sustain 2 months of "crap" without issues. Too bad for all the cool stuff we gonna miss but there is always next year. I mean a whole baseball season was thrown away cause of a mid season lockout, so sports will survive, it may just not have a stanley cup or world series winner in 2020... Yes the economy is hit but hopefully it will recover.
But by those 2 months, lets say end of May, im expecting Quebec to be ready to "re-open" at least locally. Im not saying re-open the borders or travels, but local businesses etc and lockdown being done. Cause peoples won't tolerate this for longer im sure. If in 2 months its still a big issue (lots of new cases still) they will think lockdown is just not working and is a waste of time, and they will go with the whole "develop imunity in society" options instead. Hopefully if China could recover, even as badly hit as they were, we can do, USA can too...
Nice article written in lay terms about developed immunity after covid-19 infection and it’s implications
im thinkin these anti body tests are gonna be key on figuring out who we can send back into work force, especially medical practitioners.
Rinzler, this article mentions nothing about a weak immunity provided by covid-19 infection but states rather it’s unknown/uncertain
https://www.nytimes.com/2020/03/25/health/coronavirus-immunity-antibodies.html
im thinkin these anti body tests are gonna be key on figuring out who we can send back into work force, especially medical practitioners.
Rinzler, this article mentions nothing about a weak immunity provided by covid-19 infection but states rather it’s unknown/uncertain
https://www.nytimes.com/2020/03/25/health/coronavirus-immunity-antibodies.html
Herd immunity “maybe”
https://www.google.ca/amp/s/www.for...us-twice-how-does-covid-19-immunity-work/amp/
https://www.google.ca/amp/s/www.for...us-twice-how-does-covid-19-immunity-work/amp/
some of the papers i provided links to before discuss how its possible that the immune response to sars-cov-2 might be similar to influenza. which means that if a vaccine is found (a big if - more about that here: https://www.theguardian.com/world/2020/mar/29/coronavirus-vaccine-when-will-it-be-ready), a new formulation might need to be administered every year
what is known is that a discernible immune response can be observed in symptomatic patients who managed to clear the virus for at least a few days. for example https://www.nature.com/articles/s41591-020-0819-2
the only convincing result so far that infection results in protective immunity is from this study with rhesus macaques that showed that when two of them were reexposed to sars-cov-2, covid-19 didn't develop: https://www.biorxiv.org/content/10.1101/2020.03.13.990226v1
question is will this immunity last? when it comes down to sars-cov-2 we don't know yet but there are some hints that it might be a challenge
already we know that respiratory rna viruses can evade the innate immune response: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959104/pdf/jin-0012-0004.pdf
a study done with convalescent sera from people who were infected with sars (the closest virus to sars-cov-2) further shows that it was moderately neutralizing: https://www.nature.com/articles/s41467-020-15562-9
we know that in people infected with sars the protective immunity doesnt last described here: https://www.jimmunol.org/content/186/12/7264.long
another issue is the potential of genetic drift. we already know that genetic drift occurs in human coronavirus OC43, a related virus which causes the common cold: https://www.nature.com/articles/srep11451
in a nutshell, it means through evolution the virus evades neutralizing antibodies that are generated after an infection. so somebody can get infected multiple time by the virus because the conformation of the major antigens keep changing. that's one of the reasons why people keep catching colds from that type of virus
its the one of the reasons that explains why every year we need a new flu vaccine. now at least the flu vaccine confers some protective immunity for a while. there are other viruses that the generation of neutralizing antibodies is not effective a producing a protective immunity because of genetic drift. hiv-1 is the best example i can think of
discussed here in the context of influenza: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007291&type=printable
an example with hiv-1: https://jvi.asm.org/content/jvi/79/4/2097.full.pdf
hopefully the immune response to sars-cov-2 over time is different and infection confers lasting protective immunity but i have doubts
what is known is that a discernible immune response can be observed in symptomatic patients who managed to clear the virus for at least a few days. for example https://www.nature.com/articles/s41591-020-0819-2
the only convincing result so far that infection results in protective immunity is from this study with rhesus macaques that showed that when two of them were reexposed to sars-cov-2, covid-19 didn't develop: https://www.biorxiv.org/content/10.1101/2020.03.13.990226v1
question is will this immunity last? when it comes down to sars-cov-2 we don't know yet but there are some hints that it might be a challenge
already we know that respiratory rna viruses can evade the innate immune response: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959104/pdf/jin-0012-0004.pdf
a study done with convalescent sera from people who were infected with sars (the closest virus to sars-cov-2) further shows that it was moderately neutralizing: https://www.nature.com/articles/s41467-020-15562-9
we know that in people infected with sars the protective immunity doesnt last described here: https://www.jimmunol.org/content/186/12/7264.long
another issue is the potential of genetic drift. we already know that genetic drift occurs in human coronavirus OC43, a related virus which causes the common cold: https://www.nature.com/articles/srep11451
in a nutshell, it means through evolution the virus evades neutralizing antibodies that are generated after an infection. so somebody can get infected multiple time by the virus because the conformation of the major antigens keep changing. that's one of the reasons why people keep catching colds from that type of virus
its the one of the reasons that explains why every year we need a new flu vaccine. now at least the flu vaccine confers some protective immunity for a while. there are other viruses that the generation of neutralizing antibodies is not effective a producing a protective immunity because of genetic drift. hiv-1 is the best example i can think of
discussed here in the context of influenza: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007291&type=printable
an example with hiv-1: https://jvi.asm.org/content/jvi/79/4/2097.full.pdf
hopefully the immune response to sars-cov-2 over time is different and infection confers lasting protective immunity but i have doubts
Interesting. I saw this on couple sources. The article says the person termed ‘patient zero’ is one among first 27 people who contracted this virus.Doc Holliday said:
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